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AP Biology/Unit 1: Chemistry of Life
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Chaperone Function and Directional Synthesis

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Which statement best explains why the directionality of protein synthesis is critical for the proper functioning of chaperone proteins?

A

Chaperones can only recognize proteins synthesized in the 5’ to 3’ direction

B

Chaperones interact with specific exposed regions as they emerge from the ribosome in a time-dependent sequence

C

The energy required for chaperone binding depends on N-terminus exposure

D

Chaperones bind exclusively to the C-terminus regardless of folding state

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