APFIVE Temperature Effects on Enzyme Function
An experiment shows that the rate of an enzymatic reaction doubles between 10°C and 20°C but decreases at temperatures above 40°C. Which molecular explanation best accounts for both of these observations?
A
Substrate binding affinity continuously increases with temperature
B
Increased molecular motion enhances collisions at moderate temperatures but disrupts protein folding at high temperatures
C
Enzyme concentration increases with temperature until 40°C
D
Cofactors are activated at 20°C but inhibited above 40°C
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