APFIVE Uncoupling Electron Transport and ATP Synthesis
Cells are treated with 2,4-dinitrophenol (DNP), a substance that allows protons to cross the inner mitochondrial membrane without passing through ATP synthase. Which of the following best explains how DNP disrupts cellular energy production?
A
It directly inhibits substrate-level phosphorylation
B
It blocks oxygen binding to cytochrome c oxidase
C
It uncouples electron transport from ATP synthesis
D
It prevents glucose from entering glycolysis
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