Competitive Inhibition in Cellular Respiration
Malonate, a competitive inhibitor of the enzyme succinate dehydrogenase, is added to a suspension of actively respiring mitochondria. Which of the following describes the most immediate consequence?
A
Increased production of acetyl-CoA
B
Enhanced electron flow through Complex I
C
Accelerated ATP synthesis at Complex V
D
Accumulation of succinate in the mitochondrial matrix
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