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AP Biology/Unit 3: Cellular Energetics
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Competitive Inhibition in the Krebs Cycle

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Scientists add a competitive inhibitor of succinate dehydrogenase to a sample of actively respiring mitochondria. Which of the following is the most likely direct result of this inhibition?

A

Accumulation of succinate and reduced FADH₂ production

B

Enhanced glycolytic flux to compensate

C

Immediate cell death due to complete ATP depletion

D

Increased rate of oxidative phosphorylation

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