APFIVE Rate-Limiting Step in a Metabolic Pathway
An enzyme in the glycolysis pathway has a catalytic rate that is significantly slower than the rates of other enzymes in the pathway. Which of the following conclusions does this observation best support?
A
The reduced speed of this enzyme implies a lack of regulatory importance, making its activity irrelevant to the pathway’s overall efficiency.
B
A lower reaction rate for one enzyme indicates that it is non-functional and that glycolysis is effectively halted.
C
The slow reaction rate demonstrates that the enzyme is unnecessary and its reaction can be bypassed through alternative metabolic routes.
D
The enzyme with the slower reaction rate likely serves as the rate‐limiting step, controlling the overall flux of glycolysis.
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