Uncoupling Electron Transport and ATP Synthesis
A student is analyzing data from an experiment where cells were exposed to 2,4-dinitrophenol (DNP), which allows protons to cross the inner mitochondrial membrane without passing through ATP synthase. Which of the following best explains why DNP disrupts cellular energy production?
A
It prevents glucose from entering glycolysis
B
It blocks oxygen binding to cytochrome c oxidase
C
It directly inhibits substrate-level phosphorylation
D
It uncouples electron transport from ATP synthesis
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