APFIVE GPCR Signal Transduction Sequence
Which of the following correctly outlines the sequence of events in a G protein-coupled receptor (GPCR) signal transduction pathway following the binding of a ligand?
A
Protein kinase activation → second messenger production → G protein activation → receptor conformational change
B
Second messenger production → receptor conformational change → protein kinase activation → G protein activation
C
Receptor conformational change → G protein activation → second messenger production → protein kinase activation
D
G protein activation → receptor conformational change → protein kinase activation → second messenger production
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