GPCR Signal Transduction Sequence
A researcher is studying a signal transduction pathway that begins with a G protein-coupled receptor. After ligand binding, which sequence correctly represents the functional roles of components in this pathway?
A
Second messenger production → receptor conformational change → protein kinase activation → G protein activation
B
Protein kinase activation → second messenger production → G protein activation → receptor conformational change
C
Receptor conformational change → G protein activation → second messenger production → protein kinase activation
D
G protein activation → receptor conformational change → protein kinase activation → second messenger production
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