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AP Biology/Unit 4: Cell Communication and Cell Cycle
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GPCR Signal Transduction Sequence
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A researcher is studying a signal transduction pathway that begins with a G protein-coupled receptor. After ligand binding, which sequence correctly represents the functional roles of components in this pathway?

A

Second messenger production → receptor conformational change → protein kinase activation → G protein activation

B

Receptor conformational change → G protein activation → second messenger production → protein kinase activation

C

G protein activation → receptor conformational change → protein kinase activation → second messenger production

D

Protein kinase activation → second messenger production → G protein activation → receptor conformational change

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