APFIVE Neurotransmitter Signaling Mutation
A mutation affects a protein involved in neurotransmitter signaling. Affected individuals show symptoms including muscle weakness that worsens with repeated use and improves with rest. The mutation most likely affects:
A
Acetylcholine receptors on the postsynaptic membrane
B
Voltage-gated calcium channels in presynaptic terminals
C
Dopamine synthesis in the substantia nigra
D
Acetylcholinesterase activity at the neuromuscular junction
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