Neurotransmitter Signaling Mutation
A genetic mutation in a protein involved in neurotransmitter signaling leads to muscle weakness that worsens with repeated use and improves with rest. Which of the following is the most likely target of this mutation?
A
Acetylcholinesterase activity at the neuromuscular junction
B
Voltage-gated calcium channels in presynaptic terminals
C
Dopamine synthesis in the substantia nigra
D
Acetylcholine receptors on the postsynaptic membrane
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