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AP Biology/Unit 4: Cell Communication and Cell Cycle
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Ras Protein Mutation and Cell Signaling

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A mutation in the GTPase domain of a Ras protein prevents the hydrolysis of GTP, a condition associated with excessive cell proliferation. Which of the following best describes the effect of this mutation on the cell signaling pathway?

A

Ras cannot bind to GTP, blocking all downstream signaling

B

Ras binds to inhibitory proteins more effectively

C

Ras remains locked in its active state, continuously signaling

D

Ras degrades more rapidly, reducing signal duration

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