APFIVE Autosomal Recessive Inheritance Pattern
A pedigree for a rare autosomal recessive disorder shows that two phenotypically normal parents have an affected child. Which of the following statements best explains this phenomenon?
A
Epigenetic modifications silence the dominant allele
B
Alternative splicing creates different protein isoforms
C
Random mutations occur during DNA replication in gametes
D
Both parents carry a mutant allele that is not expressed phenotypically
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