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AP Biology/Unit 6: Gene Expression and Regulation
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5' Cap Mutation and Evolutionary Selection

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A mutation arises in a gene encoding a protein essential for forming the 5’ cap on mRNA. If this mutation were to spread throughout a population, which of the following represents the most likely evolutionary consequence?

A

Neutral selection as alternative RNA processing emerges

B

Strong negative selection due to reduced protein synthesis

C

Positive selection due to increased transcription rates

D

Balancing selection maintaining both alleles

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