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AP Biology/Unit 6: Gene Expression and Regulation
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Antibiotic Stress and Bacterial Mutation

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Bacteria exposed to sublethal doses of antibiotics often exhibit higher mutation rates compared to unexposed bacteria. Which of the following best explains this observation?

A

Direct mutagenic effect of antibiotics on bacterial DNA

B

Horizontal transfer of mutated genes between bacteria

C

Selection for pre-existing hypermutator strains

D

Stress-induced activation of error-prone DNA polymerases

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