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AP Biology/Unit 6: Gene Expression and Regulation
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Transcription of Overlapping Genes

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In a specific DNA region, genes A and B have overlapping sequences and are transcribed from opposite strands. What is a potential molecular challenge that arises from this arrangement?

A

Simultaneous transcription could cause polymerase collision

B

RNA polymerase cannot bind to overlapping promoters

C

Only one gene can be functional at a time

D

Template strands must switch during transcription

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