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AP Biology/Unit 6: Gene Expression and Regulation
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Translation Without a Stop Codon

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An mRNA transcript lacking a stop codon is introduced into a cell-free protein synthesis system. Which of the following is the most likely outcome?

A

Translation will terminate at the 5’ end of the mRNA

B

Ribosomes will detach randomly along the transcript

C

Protein synthesis will not initiate at all

D

Ribosomes will remain attached to the mRNA indefinitely

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