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AP Biology/Unit 7: Natural Selection
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Geographic Distribution of the HbS Allele

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A population genetics study reveals that the HbS allele frequency varies from 0.01-0.20 across different regions of Africa. Which statement best explains this geographic distribution?

A

Gene flow has been restricted between populations

B

The mutation rate of HbS varies by region

C

Selection pressure varies with malaria prevalence

D

Random genetic drift caused regional differences

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