APFIVE Thermodynamics of Enzyme Substrate Binding
The binding of an enzyme to its substrate often involves multiple noncovalent interactions. If the ΔH° for the binding process is -15 kJ/mol and the ΔS° is -40 J/(mol·K) at 298 K, which type of noncovalent interaction is MOST likely driving this binding?
A
Hydrophobic interactions
B
Hydrogen bonding
C
Ionic interactions
D
London dispersion forces
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