APFIVE Benzodiazepine Withdrawal and Neuroadaptation
A patient develops a life-threatening condition following the abrupt cessation of benzodiazepine use. This scenario best illustrates which of the following neuroadaptive processes?
A
Sensitization to the drug’s rewarding properties
B
Downregulation of GABA receptors during chronic use
C
Cross-tolerance with other depressants
D
Permanent damage to inhibitory neurons
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