SSRI Therapeutic Delay Mechanism
A patient taking an SSRI antidepressant experiences changes in mood after several weeks of treatment. Which neural adaptation most likely explains the delayed therapeutic effect?
A
Direct stimulation of postsynaptic receptors
B
Immediate increase in synaptic serotonin levels
C
Downregulation of autoreceptors on presynaptic neurons
D
Rapid growth of new serotonergic neurons
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