SSRI Therapeutic Delay Mechanism
The therapeutic effects of SSRI antidepressants often manifest only after several weeks of treatment. This delay is most likely explained by which of the following neural adaptations?
A
Direct stimulation of postsynaptic receptors
B
Immediate increase in synaptic serotonin levels
C
Downregulation of autoreceptors on presynaptic neurons
D
Rapid growth of new serotonergic neurons
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