APFIVE Limitation of a Single-Sample Study
A researcher claims a new medication reduces average cholesterol levels. After treatment, 25 patients had a mean reduction of 12 mg/dL with standard deviation 15 mg/dL. The test statistic is t = 4.00 with p-value = 0.0003. Which limitation most affects the statistical reasoning?
A
The p-value is too small to be meaningful.
B
The sample size is too large to detect meaningful effects.
C
The study lacks a control group for comparison.
D
The standard deviation indicates the treatment is ineffective.
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